Endocrine Abstracts

Thyroid hormones (TH)s have as a major target the heart, where they regulate many different functions, including the modulation of the heart rate and myocyte contractility. Their effects on ventricular repolarization are controversial and QT prolongation was reported both in patients with hypothyroidism and hyperthyroidism, in their overt or subclinical forms. We analyzed the effects of 3.3',5.5'-tetraiodo-L-Thyronine (T4), 3.3',5-triiodo-L-Thyronine (T3) and of 3.3',5'-triiod...